ESA-backed innovation announces FDA clearance and live clinical trials in the UK.

UK-based company Adaptix, who developed a pioneering portable 3D X-ray imaging system with support from ESA’s Business Applications and Space Solutions (BASS) programme and the UK Space Agency, has announced two major milestones: FDA 510(k) clearance for its Adaptix Ortho350 Imaging System and the start of live clinical trials on patients at the Royal Devon University Healthcare NHS Foundation Trust in Exeter.

The Adaptix Ortho350 system delivers high-quality, low-dose 3D imaging for orthopaedic applications. It enables clinicians to obtain a stack of detailed diagnostic slices through the patient with a far higher level of accuracy than 2D X-rays.  Unlike CT scanners it is a portable solution which is particularly beneficial in remote or resource-limited settings, reducing delays and improving access to care.

The recent FDA clearance marks a critical step towards commercial deployment in the United States, validating the system’s safety and effectiveness. Meanwhile, clinical trials in Exeter are assessing its real-world performance, focusing on workflow efficiency and patient outcomes.

“This achievement demonstrates how space-derived technologies can deliver tangible benefits on Earth,” said Arnaud Runge, Technical Officer for ESA on the project. “We are very pleased to have supported this project from the early days and to see it achieve commercial and technical success across multiple markets. The low radiation dose and compactness of the system also mean we could even see Adaptix Ortho350 used in space in the future.”

Dr Paul Bate, CEO of the UK Space Agency said: “This progress shows the impact of collaboration between space and healthcare in driving innovation. By applying techniques originally developed for space, Adaptix is helping clinicians access faster, safer and more accurate diagnostics, directly benefiting patients and improving recovery pathways. We’re proud to have supported this journey through our partnership with ESA and look forward to seeing this technology improve patient outcomes across the UK and beyond.”

Sarah Small, CEO at Adaptix, said: “Securing this FDA 510(k) clearance represents a significant milestone for Adaptix in our mission to transform radiology. We already have a great deal of interest from healthcare providers and clinicians and are looking forward to delivering “3D-First” enhanced orthopaedic DT imaging across Primary Care, Intensive Care and Emergency Departments throughout the US and beyond.”

Adaptix’s imaging technology grew out of methods originally developed for space applications, ensuring compliance with stringent healthcare standards while maintaining portability and cost-effectiveness. It is already in use across the veterinary and non-destructive testing sectors and has also delivered positive results in human cadaver trials. The trial in Exeter is focusing on patients with inflammatory arthritis and will evaluate the performance of the Adaptix 3D imaging technology when compared to traditional 2D X-rays, focusing on three main areas: diagnostic potential, effective measurement of joint space and evaluation of bone density.

“Up to 30% of people with early rheumatoid arthritis are missed when diagnosed using 2D X-rays, but more-detailed 3D imaging – such as MRI and CT scans – is expensive and waiting lists can be long,” said Dr. Siân Phillips, Chief Medical Officer at Adaptix. “The compact design and lower radiation and power requirements of the Adaptix Ortho350 make 3D imaging much more accessible for clinicians and patients alike. These new trials mark an exciting new stage of our journey, not only delivering a clinical assessment of its effectiveness when compared to traditional 2D X-ray modalities, but also proves our range of clinical use cases from diagnostics to assessing disease progression.”

With regulatory approval secured and clinical trials underway, Adaptix is now preparing for commercial rollout in the US, paving the way for a new era of accessible diagnostic imaging worldwide. Looking ahead, CE marking for the system is also in progress, opening the door for commercialisation across Europe in 2026.

UK tech company Secure Innovation has launched its Remote Planet platform, a new service which uses space technology to provide remote management and monitoring of high value assets and infrastructure. The service, developed under ESA’s Business Applications and Space Solutions (BASS) programme, offers customisable round-the-clock protection solutions for cash, logistics, critical assets and valuable assets in even the most remote locations, and is capable of safeguarding people in high-risk locations.

Managing high value assets securely and efficiently is increasingly challenging for businesses, especially those operating in hard-to-reach areas. Remote Planet offers a single, easy-to-use platform with custom reporting tools for businesses. As part of the project with ESA, the system was tested across three continents and successfully demonstrated a dual-directional command and monitoring capability able to offer exceptional uptime for customers using the service.



The geo-location settings are a key feature of the new service. Global Navigation Satellite Services (GNSS) provide a location fix down to just 5 metres for accurate visibility. By harnessing a range of space technology and, crucially, the judicious use of data via a global Lower Earth Orbit (LEO) communication network to ensure seamless coverage when GNSS services are unreliable, Remote Planet is able to offer worldwide connectivity. The platform switches seamlessly to and from 4G when connectivity is threatened, resulting in ultra-high uptime levels. 

As well as providing geo-location settings, the real time service means that protection settings can be changed according to time, location or status. It allows businesses to react quickly to changing landscapes, and the system also has the capacity to interpret sensor readings and send messages automatically, anticipating unforeseen events which might cause harm.

By developing the software for the new system alongside its proprietary hardware, Secure Innovation Group has been able to develop a smart system that can be quickly and efficiently adapted and refined according to user requirements, without waiting for third party development rollouts and whilst still remaining compatible with mainstream systems. After sales support is a crucial element of the Remote Planet offering, with connectivity and IoT technology sitting alongside the hardware.

Marco Sartori, ESA Technical Officer on the Remote Planet project said “This has been a really interesting project, focusing on developing not only the software but also evolving the proprietary hardware, enabling a full service agile platform with the capacity and flexibility to react quickly to customer requirements.” 

The Remote Planet optimised service helps save businesses time by reducing the need for unnecessary site visits which have an impact on the environment, and its enhanced security features mean that it is also cost effective. Now operating in 15 countries across five continents, the platform already protects and monitors thousands of assets daily, valued at over £100 billion. Secure Innovation, based in Cornwall (in the far southwest of the UK) has, through the collaboration with ESA, reinforced its position as a major employer in the area, and is now equipped to expand further.  

“As a leading technology business, already securing cash and valuable assets in over 40 countries, Remote Planet has enabled Secure Innovation Group to bring flexible space-based IOT connectivity directly to assets over a wide range of industries across the globe” said Anthony McAndrew, Director of Connectivity at Secure Innovation.  “The collaboration with ESA has been a fantastic experience, and it has enabled us to grow our business reach to existing customers in the secure logistics market, as well as adjacent markets.  It’s exciting to consider the sheer range of solutions we can now provide to a myriad of customers anywhere on the planet through the Remote Planet platform.”

With the aviation sector accounting for around 2.5% of global CO2 emissions, developing smarter and greener practices for airlines and associated industries is both a major challenge and a global imperative. As part of the European Space Agency’s Business Applications and Space Solutions (BASS) programme and supported by the UK Space Agency (UKSA), UK green aerospace company SATAVIA has successfully completed a Demonstration Project involving contrail management trials with multiple airlines. The atmospheric modelling platform developed in the project has the potential to significantly reduce the impact of air travel on the environment. 

In 2021, the United Nations IPCC Climate Impact Report stated that aviation’s non-CO2 climate impacts constituted a highly significant component of the sector’s overall climate footprint, largely due to the creation of aircraft condensation trials (contrails). Contrails form at high altitudes when water vapour from aircraft engine exhaust freezes into ice crystals. Contrails mostly dissipate quickly, but in some conditions they can persist for many hours. These contrails can trap heat from the Earth, especially at night when sunlight is absent, thus contributing to atmospheric global warming. Using a conservative metric (GWP100), aircraft contrails account for more than half the climate impact of aviation’s CO2 footprint. 

The SATAVIA DECISIONX:NETZERO project saw an evolution of the company’s core DECISIONX technology, developed under an earlier project with ESA BASS, which used airborne contaminant, satellite and aircraft datasets to optimise jet engine maintenance cycles (leading to potential for 9% increase in time-on-wing and saving up to $55K per aircraft per year). Building on this core technology, SATAVIA coupled numerical weather prediction modelling with per-flight contrail climate impact modelling. This approach enables the identification of individual flights which are likely to form persistent warming contrails, in turn enabling navigational avoidance and climate benefit calculations. Leveraging this technological capability, the project set out to demonstrate that contrail management is operationally possible and offers credible non-CO2 climate impact savings.

SATAVIA engaged twelve airlines including Condor, Icelandair, and SunExpress for the next stage of the project, deploying its sophisticated atmospheric modelling technology to optimise 65 flights for contrail management. The technology was able to identify airspace where warming persistent contrails are most likely to form and, as a consequence, optimise flight plans in real time to prevent this taking place. These trials saw an average reduction in non-CO2 climate impact of >40 tonnes of carbon dioxide equivalent (T/CO2e) per optimised flight, with a total prevented climate impact of more than 2,200 T/CO2e in total. Interestingly, this flight optimisation saw minimal impact upon flight times and fuel consumption, especially during long haul flights.

“The trials conducted during the project were very positive.  All the airlines involved took this project very seriously throughout and the funding from ESA made it possible for SATAVIA to engage a larger number of airlines, resulting in a wider data range,” said Arnaud Runge, Technical Officer at the European Space Agency, who also holds an airline pilot license. “The trials were vital in highlighting how space technologies can support the environmental efforts being made in aviation, at a challenging time for the sector.” 

 

Dr Craig Brown, Director of Investment at the UK Space Agency, said: “We know that aviation is a key contributor to carbon emissions, so it’s vital to explore how technologies such as greener fuels can address this. The results from the DECISIONX trials – which used ESA’s Earth observation data for atmospheric modelling  – demonstrate how fundamental the use of space is to this global ambition. SATAVIA’s technology could make a significant impact on the voluntary carbon market, boosting opportunities for aviation sector investment in the UK, while supporting major industry initiatives against climate change.”

For the first time in the sector, 2025 will see the introduction of mandatory monitoring, reporting, and verification (MRV) of aviation’s non-CO2 impacts (including contrails) under the European Union Emission Trading Scheme (EU ETS), as the commercial aviation sector looks to mitigate the damaging effects of contrails, soot, nitrous oxides, and other non-CO2 effects. By the end of 2027, the European Commission will also submit a report that may lead to mandatory contrail avoidance within relevant territories. Alongside these policy developments, SATAVIA has patented a new methodology to generate future voluntary carbon credits from contrail management and provide financing for contrail management in advance of regulation. The method is currently undergoing design certification with Gold Standard, following concept approval in August 2023, and – once approved – will help to scale contrail management across commercial aviation.

Dr Adam Durant, who founded SATAVIA in 2013, said “This new voluntary carbon market will be worth billions of dollars globally, creating a bottom-line rationale for operators to cut their non-CO2 climate footprint in the absence of regulation. As a low-cost, easy-to-implement software solution, contrail management can help move aviation towards climate-neutral operation on near-term timescales. UKSA and ESA support for action on contrails is driving progress in this hard-to-abate industry.”

Looking to the future, SATAVIA aims to build on the success of this ESA BASS project with further R&D activity, including via collaborations with air navigation service providers (ANSPs) to identify challenges and opportunities for scaling contrail management within routine commercial aviation.